AAFM Boards Dermatology Practice Test

Surgical excision is generally regarded as the first-line treatment for squamous cell carcinoma (SCC) because it effectively removes the cancerous tissue while ensuring a margin of healthy tissue to minimize the risk of recurrence. This method allows for direct evaluation of the tumor and margins, which is vital for determining whether the cancer has been completely excised.

Surgical excision is particularly favored for localized tumors as it offers the highest chance of cure, especially when the cancer has not invaded deeper structures. Compared to other treatment options, surgical excision provides a definitive diagnosis through histopathological evaluation of the excised tissue, ensuring that any potential complications or progression of the disease can be promptly addressed.

Other treatments, such as cryotherapy, chemotherapy, or topical ointments, may be used for superficial or less aggressive forms of SCC or in patients who are not surgical candidates. However, surgical excision remains the gold standard when it comes to managing most cases of SCC effectively.